Upper gastrointestinal cancer in its early stages is predominantly asymptomatic

CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract

The mechanisms underlying CD4(+) T cell depletion in human immunodeficiency virus (HIV) infection are not well understood. Comparative studies of lymphoid tissues, where the vast majority of T cells reside, and peripheral blood can potentially illuminate the pathogenesis of HIV-associated disease. Here, we studied the effect of HIV infection on the activation and depletion of defined subsets of...

Cancer of the upper gastrointestinal tract.

Upper Gastrointestinal Cancer and Reflux Disease

There is a growing evidence that gastroesophageal reflux disease is related to several upper gastrointestinal cancers, mainly the esophageal adenocarcinoma and a certain type of gastric cardia adenocarcinoma. Currently, the incidence of gastroesophageal reflux disease is rapidly increasing in Korea. Therefore, there is a possibility of such increasing cancerous incidents, similar to the western...

Management of Upper Gastrointestinal Bleeding:what Is New?

Pharmacotherapy has focused on the use of profound acid suppression with proton-pump inhibitors in the treatment of patients with nonvariceal upper gastrointestinal hemorrhage. Experimental data have shown that gastric acid impairs clot formation, promotes platelet disaggregation, and favors fibrinolysis. The pharmaco therapeutic goal post haemostasis is therefore to achieve an intragastric pH>...

Early esophagogastroduodenoscopy is associated with better Outcomes in upper gastrointestinal bleeding: a nationwide study

Background and study aims We analyzed NIS (National Inpatient Sample) database from 2007 - 2013 to determine if early esophagogastroduodenoscopy (EGD) (24 hours) for upper gastrointestinal bleeding improved the outcomes in terms of mortality, length of stay and costs. Patients and methods Patients were classified as having upper gastrointestinal hemorrhage by querying all diagnostic codes for t...